Karl E Anderson Selected Research

Acute Intermittent Porphyria (Porphyria, Acute)

1/2022	Hereditary Coproporphyria Mimicking Guillain-Barré Syndrome After COVID-19 Infection.
1/2021	Expanding Experience With Liver Transplantation in Acute Intermittent Porphyria.
11/2020	Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
1/2020	Evaluating the Patient-Reported Outcomes Measurement Information System scales in acute intermittent porphyria.
11/2019	Acute hepatic porphyrias: Current diagnosis & management.
11/2019	International Porphyria Molecular Diagnostic Collaborative: an evidence-based database of verified pathogenic and benign variants for the porphyrias.
1/2019	Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.
6/2017	Effects of hemin and hemodialysis in a patient with acute intermittent porphyria and renal failure.
6/2015	Liver Transplantation for Acute Intermittent Porphyria: Biochemical and Pathologic Studies of the Explanted Liver.
9/2006	Open-label study of hemin for acute porphyria: clinical practice implications.

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Karl E Anderson Research Topics

Disease

15	Porphyrias (Porphyria) 01/2022 - 01/2006
13	Acute Intermittent Porphyria (Porphyria, Acute) 01/2022 - 09/2004
9	Erythropoietic Protoporphyria 01/2021 - 06/2002
7	Porphyria Cutanea Tarda 11/2019 - 02/2002
4	Infections 01/2022 - 02/2002
4	Neoplasms (Cancer) 01/2021 - 07/2005
3	Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency) 01/2022 - 01/2006
3	Pain (Aches) 11/2020 - 03/2005
3	Hepatic Porphyrias (Hepatic Porphyria) 11/2019 - 10/2017
3	Hemochromatosis (Bronze Diabetes) 11/2019 - 02/2002
3	HIV Infections (HIV Infection) 03/2011 - 02/2002
2	Paresis (Hemiparesis) 01/2022 - 03/2005
2	Body Weight (Weight, Body) 11/2020 - 01/2019
2	Phototoxic Dermatitis (Phototoxicity) 01/2019 - 08/2010
2	Liver Diseases (Liver Disease) 09/2018 - 04/2013
2	Lead Poisoning (Poisoning, Lead) 12/2015 - 09/2004
2	Hepatitis C 03/2011 - 02/2002
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2009 - 02/2009
2	Breast Neoplasms (Breast Cancer) 03/2008 - 07/2007
1	Rare Diseases (Rare Disease) 01/2022
1	COVID-19 01/2022
1	Lithiasis 01/2022
1	Neurologic Manifestations (Neurological Manifestations) 01/2022
1	Carcinogenesis 01/2021
1	Metabolic Diseases (Metabolic Disease) 01/2021
1	Polycythemia Vera 12/2020
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 12/2020
1	Disease Progression 12/2020
1	Hyperbilirubinemia 12/2020
1	Injection Site Reaction 11/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2020
1	Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency) 11/2019
1	Hypoxia (Hypoxemia) 11/2019
1	Hepatoerythropoietic Porphyria 11/2019
1	Myocardial Infarction 12/2018
1	Stroke (Strokes) 12/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2018
1	Pulmonary Embolism 12/2018
1	Renal Insufficiency (Renal Failure) 06/2017
1	Liver Failure 02/2016
1	Hyperplasia 06/2015
1	Inflammation (Inflammations) 12/2010
1	Chronic Disease (Chronic Diseases) 12/2010
1	Fibrosis (Cirrhosis) 08/2010

Drug/Important Bio-Agent (IBA)

12	Heme (Haem)IBA 01/2022 - 03/2005
7	EnzymesIBA 01/2022 - 10/2017
7	protoporphyrin IXIBA 12/2020 - 06/2002
6	PorphyrinsIBA 01/2022 - 08/2010
6	Hemin (Panhematin)FDA Link 12/2020 - 03/2005
5	Ferrochelatase (Heme Synthetase)IBA 01/2021 - 06/2002
5	Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)IBA 11/2019 - 02/2002
4	Acute Hepatic PorphyriaIBA 01/2022 - 01/2020
4	PorphobilinogenIBA 11/2020 - 01/2006
3	Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)IBA 01/2022 - 01/2006
3	givosiranIBA 01/2022 - 01/2019
3	Aminolevulinic Acid (Levulan)FDA Link 12/2020 - 09/2018
3	AcidsIBA 12/2020 - 09/2004
3	IronIBA 11/2019 - 12/2012
3	Estrogens (Estrogen)FDA Link 03/2011 - 02/2002
2	Hydro-Lyases (Dehydratases)IBA 12/2020 - 01/2006
2	Adenosine Diphosphate (ADP)IBA 12/2020 - 04/2006
2	IsoflavonesIBA 12/2018 - 07/2005
2	Ethanol (Ethyl Alcohol)IBA 03/2011 - 03/2010
2	Glucose (Dextrose)FDA LinkGeneric 06/2009 - 03/2005
2	SteroidsIBA 06/2009 - 02/2009
2	Biomarkers (Surrogate Marker)IBA 03/2008 - 07/2007
1	PorphyrinogensIBA 01/2022
1	fibulin 2IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Tamoxifen FDA LinkGeneric 01/2021
1	IntegrinsIBA 01/2021
1	Conditioned Culture MediaIBA 01/2021
1	Transaminases (Aminotransferases)IBA 11/2020
1	CreatinineIBA 11/2020
1	GasesIBA 11/2019
1	Isoniazid (Ftivazide)FDA LinkGeneric 11/2019
1	Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA 11/2019
1	Protoporphyrinogen Oxidase (Protox)IBA 11/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	CalciumIBA 12/2018
1	Biological ProductsIBA 02/2016
1	MetalsIBA 12/2015
1	zinc protoporphyrinIBA 12/2015
1	afamelanotideIBA 07/2015
1	Melanocyte-Stimulating Hormones (MSH)IBA 07/2015
1	hydroxymethylbilaneIBA 06/2015
1	5-Aminolevulinate SynthetaseIBA 04/2013
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2012
1	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 03/2011
1	C-Reactive ProteinIBA 12/2010

Therapy/Procedure

3	Therapeutics 01/2021 - 01/2019
2	Liver Transplantation 01/2021 - 06/2015
1	Intravenous Administration 11/2020
1	RNAi Therapeutics 11/2020
1	Subcutaneous Injections 01/2019
1	Injections 01/2019
1	Renal Dialysis (Hemodialysis) 06/2017
1	Appendectomy 12/2014
1	Cholecystectomy 12/2014
1	Aftercare (After-Treatment) 08/2010